Informatics Research Seminar: Applied Bioinformatics for Organizations and Operations

April 18, 2018 - 4:00 PM to April 19, 2018 - 4:59 PM
Presented from UNC-Chapel Hill; Watch at UNC Charlotte in Fretwell 126

Speaker: Kimberly Robasky, PhD

Location: The seminar is at UNC Chapel Hill, but UNC Charlotte students can participate live in Fretwell 126

Abstract: Some estimates place the cost of bringing a drug to market at one billion U.S dollars and hence reducing the cost and length of clinical trials can indirectly lower healthcare costs. One source of clinical trial failure, lack of efficacy and safety, could be mitigated through decision support for patient stratification.  As part of the NIH-funded Biomedical Data Translator project, we are integrating multiple, previously disparate datasets, which is empowering investigators with new tools for data-driving patient subtyping. For example, through the Data Translator project, we can combine clinical records with exposure data in support of powerful models for classification. We have implemented supervised and unsupervised machine learning models on these data for predicting patient outcomes according to exposure in order to better understand patient disease and response.